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| Links to reprints of papers from these and other projects can be found on the download page. | |||
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Genomic Analysis in Zebrafish Development The goal of this project is to develop a database of human genes that have two corresponding genes ("co-orthologs") in zebrafish, i.e. the three genes are all descended from the same gene in an ancient vertebrate that is the most recent common ancestor of fish and humans. In many cases the various functions of the human gene will be partitioned among the two zebrafish genes, and by studying these genes in isolation researchers may gain a better understanding of the human gene. |
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tRNA DataMart The tRNA DataMart is a web-based repository of bacterial tRNA genes. The DataMart provides a high-level, domain-specific interface to the data: users specify items they want by interacting with familiar displays (e.g. species names organized by taxonomic categories), and reports generated by the system are returned in standard formats that allows the data to be imported into a variety of applications for further analysis. |
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Evolution of Introns This project will investigate the origin of introns and the question of why they havebeen maintained over millions of years of natural selection through a series of comparative genomics studies of spliceosomes, the complexes of RNA and protein that transform gene transcripts containingintrons into mature mRNA molecules that can be translated into proteins |
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Rule-Based Workflow Large-scale bioinformatics projects use workflow management systems to coordinate a wide variety of applications, including sequence database searches, pairwise and multiple alignment programs, phylogenetic tree builders, and more. This project is developing a new method for organizing bioinformatic workflows using a simple rule-based methodology: project steps are defined by rules for producing workflow products, and the system automatically schedules steps using dependences between products. |
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http://chinook.uoregon.edu/gallery.html |
Neural Models of Chemotaxis in Caenorhabditis elegans In this project we are building artificial neural networks as models of the neural systems in nematode worms that are responsible for chemotaxis (movement in response to detection of chemicals in the environment). C. elegans have two sensory neurons, and our models show that worms respond to a change in the concentration of the chemical attractant detected by the input neurons. |
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